The fixed dose combination of polymyxin B sulphate, bacitracin zinc and neomycin sulphate is used topically in the treatment of dermatological diseases of mixed infection.
Ingredients: Polymyxin B Sulphate 5000 u + Bacitracin Zinc 400 u + Neomycin Sulphate 3400 u
Packing: 1 Pcs/Phile
Dosage: As directed by physician.
Precautions: Kidney or liver disease, neuromuscular disorders(e.g. myasthenia gravis, parkinsonism), impaired hearing(pre-existing vertigo, tinnitus, hearing loss). Monitor auditory and renal function in patients with additional risk factors. Monitor patients on high doses or prolonged courses. elderly patients, lactation, dehydrated patients. Avoid prolonged use.
Contraindications: Do not use for intestinal disinfection if there is intestinal obstruction, hypersensitivity to aminoglycosides, infants below of 1 year. Inflammatory or ulcerative GI disease(oral), pregnancy. Do not administer parenterally or as peritoneal lavage.
Oral: Nausea, diarrhoea, vomiting, irritation or soreness of the mouth or rectal area, dyspnoea, eosinophilia, nephrotoxicity, neurotoxicity, ototoxicity(auditory and vestibular).
Topical: Contact dermatitis. Potentially Fatal: Neuromuscular blockade and respiratory paralysis.Oral: Nausea, diarrhoea, vomiting, irritation or soreness of the mouth or rectal area, dyspnoea, eosinophilia, nephrotoxicity, neurotoxicity, ototoxicity(auditory and vestibular).
Drug Interaction: Synergistic effects with penicillins. Additive toxicity with neurotoxic, ototoxic or nephrotoxic drugs. May decrease absorption of digoxin and methotrexate. May increase effects of oral anticoagulants.
Storage Conditions: Store it at room temperature and in an airtight container. Keep away from light and children.