The fixed dose combination (FDC) of betamethasone valerate (a corticosteroid ) and neomycin sulfate (a broad spectrum antibiotic), is used in many local bacterial infections and infective inflammation of skin and mucosa.
Ingredients: Betamethasone Dipropionate 0.05% + Neomycin Sulphate 0.5% + Zinc Sulphate 0.5%
Packing: 1 Tube/Pack
Adults: As betamethasone (valerate) ointment 0.122% w/w+ neomycin sulfate 0.5% w/w: Apply onto the affected area(s) 2-3 times daily.
Children: =2 years: As cream/ointment containing betamethasone (as valerate) 0.122% w/w+ neomycin sulfate 0.5% w/w: Apply in affected area(s) 2-3 times daily. Usual treatment duration: Up to 5 days/course.
Precautions: Avoid prolonged treatment as it may lead to systemic corticosteroid effects even without occlusion, avoid prolonged excessive application to the facial areas, risk of glaucoma development if preparation enters eye(s), regular monitoring is recommended when used in psoriasis due to treatment tolerance, rebound relapses, generalised pustular psoriasis or systemic toxicity, increased risk of contact sensitisation when used for extended period or recurrently, pregnancy and lactation, Ophthalmic preparation: monitor intraocular pressure, cataract formation of unsuspected infections, evaluate treatment if there is no clinical improvement after 7 days.
Contraindications: Hypersensitivity, rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus and primary cutaneous viral infections, not to be used in otitis externa complicated by ear-drum perforation Primary or secondary infections due to yeast, or secondary infections due to pseudomonas or proteus species, children <2 years, ophthalmic preparation:not to be used in patients with glaucoma or herpetic keratitis.
Side Effects: Prolonged use may cause local atrophic changes in the skin eg., thinning, striae and dilatation of superficial blood vessels, local skin burning sensation, pruritus, pigmentation changes, allergic contact dermatitis and hypertrichosis, Ophthalmic preparation: corneal ulceration, increased intraocular pressure, mydriasis, ptosis, epithelial punctate keratitis.
Storage Conditions: Store it at room temperature and in an airtight container. Keep away from light and children.